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Ro 5212773

CAS No. 1110781-88-8

Ro 5212773 ( EPPTB; Epptb; Ro 5212773 )

Catalog No. M28628 CAS No. 1110781-88-8

EPPTB is a selective TAAR1 antagonist.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Ro 5212773
Note

Research use only, not for human use.
Brief Description

EPPTB is a selective TAAR1 antagonist.
Description

EPPTB is a selective TAAR1 antagonist.(In Vivo):EPPTB prevents the reduction of the firing frequency of DA neurons induced by p-tyramine (p-tyr), a nonselective TAAR1 agonist. the EPPTB effects were absent in Taar1 knockout mice, ruling out off-target effects.
Synonyms

EPPTB; Epptb; Ro 5212773
Pathway

Others
Target

Other Targets
Recptor

EGFR
Research Area

——
Indication

——

Chemical Information

CAS Number

1110781-88-8
Formula Weight

378.4
Molecular Formula

C20H21F3N2O2
Purity

>98% (HPLC)
Solubility

——
SMILES

CCOc1cccc(NC(c(cc2)cc(C(F)(F)F)c2N2CCCC2)=O)c1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.John Emmerson Campbell, et al. Inhibitors of mutant forms of egfr. Patent WO2021133809A1.

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